NEXT GENERATION PROTEOMICS WITH DRUG SENSITIVITY SCREENING IDENTIFIES SUB-CLONES INFORMING THERAPEUTIC AND DRUG DEVELOPMENT STRATEGIES FOR MULTIPLE MYELOMA PATIENTS

Abstract With the introduction of novel therapeutic agents, survival in Multiple Myeloma (MM) has increased in recent years.However, drug-resistant clones inevitably arise and lead to disease progression and death.The current International Myeloma Working Group response criteria are broad and make it difficult to clearly designate resistant and res

Agar pelayanan yang dilakukan di bagian administrasi mahasiswa Fakultas Sains dan Teknologi UIN SUSKA Riau dapat memenuhi keinginan mahasiswa maka dilakukan perbaikan kualitas yang menitikberatkan pada pemenuhan keinginan mahasiswa.Perbaikan kualitas menggunakan metode Quality Function Deployment dapat menerjemahkan keinginan mahasiswa ke dalam tin

The endohedral metallofullerenol Gd@C82(OH)22 has been identified as a possible antineoplastic agent that can inhibit both the growth and metastasis of cancer cells.Despite these potentially important effects, our understanding of the interactions between Gd@C82(OH)22 and biomacromolecules remains incomplete.Here, we study the interaction between G

Abstract The Trinket Tray classical conservation of the lepton number is an accidental symmetry present in the Standard Model (SM).Thus, we consider here a scenario where the SM is extended with a U(1) gauge group, promoting the lepton number to a local symmetry.The gauge anomaly cancellations necessitate the extension of the particle spectrum with

Abstract Background In crosses between the proline-deficient mutant homozygous for p5cs1 and heterozygous for p5cs2 (p5cs1 p5cs2/P5CS2), used as male, and different Arabidopsis mutants, used as females, the p5cs2 mutant allele was rarely transmitted to the outcrossed progeny, suggesting that the fertility of the male gametophyte carrying mutations